Pelvic inflammatory disease in the era of the Microbiome Project and evolving antimicrobial resistance: implications for clinicians

Dr Jeanne Marrazzo

Pelvic inflammatory disease (PID) remains a challenge for clinicians in terms of the diagnosis and proper management. Declines in chlamydia and gonorrhea incidence in most parts of the world have likely resulted in declines in PID related to these organisms, yet challenges remain. What is the contribution of anaerobes, especially those arising from vaginal bacteria? How should gonorrhea be covered with antibiotic regimens that address this organism’s ever-evolving capacity for resistance? Are there better ways to diagnose this condition, and anything new in prevention? Finally, is there a role for “new” pathogens, like M. genitalium, in helping us to understand what PID is and how best to treat it?

 

2011 Australasian Sexual Health Conference 'Sex in the City', recorded in September 2011 Canberra, Australia.

Jeanne Marrazzo
Jeanne Marrazzo
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VideoPelvic inflammatory disease in the era of the microbiome project and evolving antimicrobial resistance: implications for cliniciansJeanne Marrazzo55'50"
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Dr Jeanne Marrazzo

Professor in the Division of Infectious Diseases at the University of Washington, in Seattle, U.S. Dr Marrazzo is Medical Director of the Seattle STD/HIV Prevention and Training Center, president of the American STD Association, and Associate Editor of the journal Sexually Transmitted Diseases. She is Protocol Co-Chair of the VOICE Study, a large study implemented by the Microbicides Trial Network to test HIV pre-exposure prophylaxis administered vaginally and orally to women at high risk for HIV infection in sub-Saharan Africa. She is a Fellow of the American College of Physicians and the Infectious Disease Society of America, and has been the Principal Investigator for numerous studies of clinical and epidemiologic aspects of genital chlamydial infections, vaginal infections, and cervicitis. Other research interests include molecular epidemiology, pathogenesis, and management of bacterial vaginosis, diagnosis and screening of chlamydial infection and epidemiology and management of cervicitis.

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